Antibiotic Guideline for GBS and PPROM

The aim of this practice resources is to provide guidance for providing antibiotics for GBS prophylaxis and with preterm prelabour rupture of membranes. The document combines recommendations from SOGC Clinical Practice Guideline No.233 – Antibiotic Therapy in Preterm Premature Rupture of the Membranes (Reaffirmed September 2017), and No.298 – The Prevention of Early-Onset Neonatal Group B Streptococcal Disease (Reaffirmed August 2018). The SOGC guidelines reflect the available evidence and professional opinion at the time of publication and are subject to change. Amendments made to the SOGC guidelines at a local level should be well documented to illustrate the basis for clinical decision-making in the course of care.